Use the “The 10 Strategic Points for the Prospectus, Proposal, and Direct Practice Improvement Project” resource to draft statements for each of the 10 points for your intended research study.

The article looks at the “Inadequacies of physical examination as a cause of medical errors and adverse events: a collection of vignettes” from the American journal of medicine. It takes into consideration the fact that, the oversights in the corporeal assessment are a medical fault which aren’t studied via chart evaluation. Furthermore, the article states that these oversights in the corporeal assessments may be the primary contributors to the neglected or late diagnosis besides unnecessary exposure to contrast as well as radiation on the Leukemia patients. Either the authors indicate that the incorrect treatments resulting from these delays leads to unfavorable results like fainting on the Leukemia patient, lack of appetite on the side of the patient, worsening the Leukemia conditions which eventually can lead to early death of the patient.

B. Hockings, J. K., Owolabi, D. K., Broyles, J. E., & Wheelis, S. C. (2017). Impact of medication administration error on over 3 years Leukemia patients and the stimulating factors in acute leukemia and stem cell transplant patients. Supportive Care in Cancer, 25(6), 1853-1858.

The authors of this article explored the “Impact of medication administration error on over 3 years Leukemia patients and the stimulating factors in acute leukemia and stem cell transplant patients.” This article is from supportive care in cancer and it was retrieved from Google Scholar. The article authors acknowledge the fact that, the medication administration errors lead to severe impacts on the health conditions of the patient more especially the ones who are 3 – 4 years of Leukemia. According to the authors, the impacts associated with the medication administration errors may lead to worsening of the health condition of the patient, the rate of Leukemia advancement into higher stages may also increase with treatment or managing of this deadly disease being more complicated. The authors argue that using erroneous medicines, the Leukemia advancement increases without the knowledge of the patient which makes even the survival chances of the patient to reduce due to stress upon realizing that there was an error in his or her medication.

C. Douer, D. (2016). Efficacy and safety of vincristine sulfate liposome injection in the treatment of adult acute lymphocytic leukemia. The oncologist, 21(7), 840-847.

This research study examines the “Efficacy and safety vincristine sulfate liposome injection in the treatment of adult acute lymphocytic Leukemia” this article is from the oncologist. The article has been retrieved from Google Scholar. The authors take into consideration on the erroneous administration of vincristine sulfate liposome injection drug which is commonly used for treatment of Leukemia more especially at the lower stages like this of 3 – 4 years. However, when this drug is misused, it leads to instant death according to the author since even when it’s correctly applied, it’s normally restricted due to neurotoxicity concerns. The author indicates that if a patient with large body surface area to volume ratio is overdosed with the drug, it will lead to death or reduction of the survival rates to almost 20% in accordance with the authors’ analysis.

D. Tavitian, S., Denis, A., Vergez, F., Berard, E., Sarry, A., Huynh, A., … & Bertoli, S. (2016). Impact of obesity in favorable‐risk AML patients receiving intensive chemotherapy. American journal of hematology, 91(2), 193-198.

The authors of this article analyze the “Impact of obesity in favorable risk AML patients receiving intensive chemotherapy” an article from American journal of hematology. The article has been retrieved from Google Scholar. According to the authors, the obesity has got negative impacts more especially to the Leukemia patients who are receiving intensive chemotherapy while trying to manage it at the earlier stages. According to the authors, the erroneous medication administration to such Leukemia patients may lead to paralysis in the earlier stages as well as earlier death if the erroneous medication isn’t recognized earlier.

E. Santoleri, F., Lasala, R., Ranucci, E., La Barba, G., Di Lorenzo, R., Vetrò, A., … & Costantini, A. (2016). Medication adherence to tyrosine kinase inhibitors: 2-year analysis of medication adherence to imatinib treatment for chronic myeloid leukemia and correlation with the depth of molecular response. Acta haematologica, 136(1), 45-51.

This last article explores “Medication adherence to tyrosine kinase inhibitors: 2-year analysis of medication adherence to imatinib treatment for chronic myeloid leukemia and correlation with the depth of molecular response.” From Acta haematologica, the article is retrieved from Google Scholar. In accordance with the authors of the article, adherence to tyrosine medication can help in the treatment of Leukemia more especially at the earlier stage of 3 – 4 years. However, the authors stresses that the erroneous administration of these drugs that are meant to cure the Leukemia, they can turn out to be a poison in the body which facilitates the advancement of the disease in the body and eventually leads to coma and consequently death.

From the above articles, various variables were identified which includes, the patients served between 4AM to 8AM experience higher rates of erroneous medication which is a time dependent variable. The second variable is on the medication ordered by practicing nurses, with resultant observation that it is very high more especially during weekends. This is an independent variable. The year of the trainee also means that a dependent variable in the last first year trainees committed many erroneous administrations of medication compared to final years trainees.

What are the impacts of medication administration errors on 3-4-Year-old Leukemia Patients?

· Target Population:

· Pediatric Hospitals/ Patients

· 3-4-Year-old Leukemia Patients

· Physicians

· Therapists

Sample: Will be composed of interviews with 5 pediatric hospitals, physicians, parents and 5 Therapists in the county.

· The number of patients seen who erroneously administered medication are – dependent variable

· Medication ordered by the trainees – independent variable

· The year the trainee is in medical practicing like first year or final year – independent variable.

· Visits to pediatric hospital facilities

· Interview with Physicians, Parents & Therapist recorded on tape

· Sampling Method: Purposeful Sampling

· Sources: Interviews, Surveys & Questionnaires

· Descriptive statistics will be used in summarizing the data collected.

· Coding will be used to address questions posed.

· A narrative summary will be developed.