Use the “The 10 Strategic Points for the Prospectus, Proposal, and Direct Practice Improvement Project” resource to draft statements for each of the 10 points for your intended research study.

DPI Project Milestone: 10 Strategic Points for the Prospectus, Proposal, and Direct Practice Improvement ProjecIn the prospectus, proposal, and scholarly project there are 10 strategic points that need to be clear, simple, correct, and aligned to ensure the research is doable, valuable, and credible. The 10 strategic points emerge from researching literature on a topic that is based on or aligned with the learner’s personal passion, future career purpose, and degree area. These 10 points provide a guiding vision for DPI Project. In this assignment, you will continue the work begun in DNP-815, working on your draft of a document addressing the 10 key strategic points that define your intended research focus and approach.

The DNP-815 10 Strategic Points-ATTACHED

In the prospectus, proposal, and scholarly project there are 10 strategic points that need to be clear, simple, correct, and aligned to ensure the research is doable, valuable, and credible. The 10 strategic points emerge from researching literature on a topic that is based on or aligned with the learner’s personal passion, future career purpose, and degree area. These 10 points provide a guiding vision for DPI Project. In this assignment, you will continue the work begun in DNP-815, working on your draft of a document addressing the 10 key strategic points that define your intended research focus and approach.h

General Requirements:

Use the following information to ensure successful completion of the assignment:

· Locate the “The 10 Strategic Points for the Prospectus, Proposal, and Direct Practice Improvement Project” that you completed in DNP-815.

· Doctoral learners are required to use APA style for their writing assignments. The APA Style Guide is located in the Student Success Center. An abstract is not required.

· This assignment uses a rubric. Please Review the rubric prior to the beginning to become familiar with the expectations for successful completion.

· You are required to submit this assignment to LopesWrite. Please refer to the directions in the Student Success Center.

Directions:

Use the “The 10 Strategic Points for the Prospectus, Proposal, and Direct Practice Improvement Project” resource to draft statements for each of the 10 points for your intended research study.

Portfolio Practice Hours:

Practice immersion assignments are based on your current course objectives, and are intended to be application-based learning using your real-world practice setting. These assignments earn practice immersion hours, and are indicated in the assignment by a Portfolio Practice Hours statement which reminds you, the learner, to enter in a corresponding case log in Typhon. Actual clock hours are entered, but the average hours associated with each practice immersion assignment is 10.

You are required to complete your assignment using real-world application. Real-world application requires the use of evidence-based data, contemporary theories, and concepts presented in the course. The culmination of your assignment must present a viable application in a current practice setting. For more information on parameters for practice immersion hours, please refer to DNP resources in the DC Network.

10 STRATEGIC POINTS 2

Ten Strategic Points

Grand Canyon University

DNP-815- O502: Scientific Underpinnings

10 Strategic Points Table

(Use this table to complete the 10 Strategic Points document for your project.)

10 Strategic Points Comments/Feedback
Broad Topic Area Impact of Medication Administration Errors on 3-4-Year-old Leukemia Patients
Literature Review A. Verghese, A., Charlton, B., Kassirer, J. P., Ramsey, M., & Ioannidis, J. P. (2015). Inadequacies of physical examination as a cause of medical errors and adverse events: a collection of vignettes. The American journal of medicine, 128(12), 1322-1324.

The article looks at the “Inadequacies of physical examination as a cause of medical errors and adverse events: a collection of vignettes” from the American journal of medicine. It takes into consideration the fact that, the oversights in the corporeal assessment are a medical fault which aren’t studied via chart evaluation. Furthermore, the article states that these oversights in the corporeal assessments may be the primary contributors to the neglected or late diagnosis besides unnecessary exposure to contrast as well as radiation on the Leukemia patients. Either the authors indicate that the incorrect treatments resulting from these delays leads to unfavorable results like fainting on the Leukemia patient, lack of appetite on the side of the patient, worsening the Leukemia conditions which eventually can lead to early death of the patient.

B. Hockings, J. K., Owolabi, D. K., Broyles, J. E., & Wheelis, S. C. (2017). Impact of medication administration error on over 3 years Leukemia patients and the stimulating factors in acute leukemia and stem cell transplant patients. Supportive Care in Cancer, 25(6), 1853-1858.

The authors of this article explored the “Impact of medication administration error on over 3 years Leukemia patients and the stimulating factors in acute leukemia and stem cell transplant patients.” This article is from supportive care in cancer and it was retrieved from Google Scholar. The article authors acknowledge the fact that, the medication administration errors lead to severe impacts on the health conditions of the patient more especially the ones who are 3 – 4 years of Leukemia. According to the authors, the impacts associated with the medication administration errors may lead to worsening of the health condition of the patient, the rate of Leukemia advancement into higher stages may also increase with treatment or managing of this deadly disease being more complicated. The authors argue that using erroneous medicines, the Leukemia advancement increases without the knowledge of the patient which makes even the survival chances of the patient to reduce due to stress upon realizing that there was an error in his or her medication.

C. Douer, D. (2016). Efficacy and safety of vincristine sulfate liposome injection in the treatment of adult acute lymphocytic leukemia. The oncologist, 21(7), 840-847.

This research study examines the “Efficacy and safety vincristine sulfate liposome injection in the treatment of adult acute lymphocytic Leukemia” this article is from the oncologist. The article has been retrieved from Google Scholar. The authors take into consideration on the erroneous administration of vincristine sulfate liposome injection drug which is commonly used for treatment of Leukemia more especially at the lower stages like this of 3 – 4 years. However, when this drug is misused, it leads to instant death according to the author since even when it’s correctly applied, it’s normally restricted due to neurotoxicity concerns. The author indicates that if a patient with large body surface area to volume ratio is overdosed with the drug, it will lead to death or reduction of the survival rates to almost 20% in accordance with the authors’ analysis.

D. Tavitian, S., Denis, A., Vergez, F., Berard, E., Sarry, A., Huynh, A., … & Bertoli, S. (2016). Impact of obesity in favorable‐risk AML patients receiving intensive chemotherapy. American journal of hematology, 91(2), 193-198.

The authors of this article analyze the “Impact of obesity in favorable risk AML patients receiving intensive chemotherapy” an article from American journal of hematology. The article has been retrieved from Google Scholar. According to the authors, the obesity has got negative impacts more especially to the Leukemia patients who are receiving intensive chemotherapy while trying to manage it at the earlier stages. According to the authors, the erroneous medication administration to such Leukemia patients may lead to paralysis in the earlier stages as well as earlier death if the erroneous medication isn’t recognized earlier.

E. Santoleri, F., Lasala, R., Ranucci, E., La Barba, G., Di Lorenzo, R., Vetrò, A., … & Costantini, A. (2016). Medication adherence to tyrosine kinase inhibitors: 2-year analysis of medication adherence to imatinib treatment for chronic myeloid leukemia and correlation with the depth of molecular response. Acta haematologica, 136(1), 45-51.

This last article explores “Medication adherence to tyrosine kinase inhibitors: 2-year analysis of medication adherence to imatinib treatment for chronic myeloid leukemia and correlation with the depth of molecular response.” From Acta haematologica, the article is retrieved from Google Scholar. In accordance with the authors of the article, adherence to tyrosine medication can help in the treatment of Leukemia more especially at the earlier stage of 3 – 4 years. However, the authors stresses that the erroneous administration of these drugs that are meant to cure the Leukemia, they can turn out to be a poison in the body which facilitates the advancement of the disease in the body and eventually leads to coma and consequently death.

From the above articles, various variables were identified which includes, the patients served between 4AM to 8AM experience higher rates of erroneous medication which is a time dependent variable. The second variable is on the medication ordered by practicing nurses, with resultant observation that it is very high more especially during weekends. This is an independent variable. The year of the trainee also means that a dependent variable in the last first year trainees committed many erroneous administrations of medication compared to final years trainees.

Problem Statement It is not known the impact of medication administration errors on 3-4-year-old leukemia patients
Clinical/PICO Questions What is the impact of medication administration errors in pediatric patients?

What are the impacts of medication administration errors on 3-4-Year-old Leukemia Patients?

Sample · Location– Harris County, Texas. USA

· Target Population:

· Pediatric Hospitals/ Patients

· 3-4-Year-old Leukemia Patients

· Physicians

· Therapists

Sample: Will be composed of interviews with 5 pediatric hospitals, physicians, parents and 5 Therapists in the county.

Define Variables To effectively understand the impact of medication administration errors on 3-4-year-old Leukemia patients, the following variables would be used.

· The number of patients seen who erroneously administered medication are – dependent variable

· Medication ordered by the trainees – independent variable

· The year the trainee is in medical practicing like first year or final year – independent variable.

Methodology and Design Qualitative Descriptive Study
Purpose Statement The purpose of this qualitative descriptive case study is to understand are the impacts of medication administration errors on 3-4-Year-old Leukemia Patients in Harris County, Texas?
Data Collection Approach · Informed & signed consent by participants

· Visits to pediatric hospital facilities

· Interview with Physicians, Parents & Therapist recorded on tape

· Sampling Method: Purposeful Sampling

· Sources: Interviews, Surveys & Questionnaires

Data Analysis Approach · Data will be collected and analyzed for the study.

· Descriptive statistics will be used in summarizing the data collected.

· Coding will be used to address questions posed.

· A narrative summary will be developed.

References

Douer, D. (2016). Efficacy and safety of vincristine sulfate liposome injection in the treatment of adult acute lymphocytic leukemia. The oncologist21(7), 840-847.

Hockings, J. K., Owolabi, D. K., Broyles, J. E., & Wheelis, S. C. (2017). Impact of medication administration error on over 3 years Leukemia patients and the stimulating factors in acute leukemia and stem cell transplant patients. Supportive Care in Cancer25(6), 1853-1858.

Santoleri, F., Lasala, R., Ranucci, E., La Barba, G., Di Lorenzo, R., Vetrò, A., … & Costantini, A. (2016). Medication adherence to tyrosine kinase inhibitors: 2-year analysis of medication adherence to imatinib treatment for chronic myeloid leukemia and correlation with the depth of molecular response. Acta haematologica136(1), 45-51.

Tavitian, S., Denis, A., Vergez, F., Berard, E., Sarry, A., Huynh, A., … & Bertoli, S. (2016). Impact of obesity in favorable‐risk AML patients receiving intensive chemotherapy. American journal of hematology91(2), 193-198.

Verghese, A., Charlton, B., Kassirer, J. P., Ramsey, M., & Ioannidis, J. P. (2015). Inadequacies of physical examination as a cause of medical errors and adverse events: a collection of vignettes. The American journal of medicine128(12), 1322-1324.

10

“Get 15% discount on your first 3 orders with us”
Use the following coupon
FIRST15

Order Now